What is Spravato®?
Spravato® (esketamine) is a prescription nasal spray approved by the FDA for adults with treatment-resistant depression or depressive symptoms in adults with major depressive disorder (MDD) and suicidal thoughts or actions.
How is Spravato® different from traditional antidepressants?
Spravato® works on the brain’s glutamate system, unlike traditional antidepressants that target serotonin, norepinephrine, or dopamine. This different mechanism can lead to faster symptom relief for some patients.
What can I expect during a Spravato® treatment session?
You’ll self-administer the nasal spray under medical supervision in our office. Each session typically lasts about two hours, including a monitoring period where we ensure you’re safe and comfortable before going home.
How often will I need treatment?
Spravato® treatment begins with twice-weekly sessions for the first four weeks, followed by a gradual tapering schedule based on your individual response and your provider’s recommendations.
Will I be able to drive after my appointment?
No. You must arrange for a trusted friend or family member to drive you home after each session. Spravato® can cause sedation or dizziness, so driving is not safe afterward.
Is Spravato® covered by insurance?
Many insurance plans do cover Spravato®, but coverage can vary. Our team will help guide you through the approval process and work with your insurance provider to determine your benefits.
How quickly will I feel better?
Some people notice improvement within hours or days, but individual results vary. A full treatment course provides the best chance for lasting relief.